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FDA Thinks Shortage of Cancer Drug for Kids Can Be Averted

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Related MedlinePlus PageAcute Lymphocytic Leukemia

TUESDAY, Feb. 14 (HealthDay News) -- The U.S. Food and Drug Administration said Tuesday that it was cautiously optimistic that a feared shortage of a life-saving drug used to treat a form of childhood leukemia will be averted.

The drug, methotrexate, is used in combination with other drugs to combat acute lymphoblastic leukemia (ALL), which typically strikes children ages 2 to 5 and is the most common type of cancer in children.

Methotrexate is a linchpin in the treatment of children battling acute lymphoblastic leukemia. In high doses, the generic drug has been successful in curing patients and beneficial in preventing recurrence. Without the drug, a patient's chance for a cure is...

Acute Lymphoblastic Leukemia (ALL) Treatment in Adults (Beyond the Basics)

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Acute lymphoblastic leukemia (ALL) is a cancer of blood cells. ALL is also known as lymphoblastic lymphoma when the disease primarily involves lymph nodes rather than the blood and bone marrow. ALL involves a type of white blood cell called a lymphocyte. Acute means that it develops and advances quickly, and requires immediate treatment.

Normally, lymphocytes and other blood cells are produced by the bone marrow (the spongy area in the middle of bones)...

Mapping the Evolution of Cancer Cells in Leukemia

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Mapping the Evolution of Cancer Cells in LeukemiaDrs. Timothy Graubert (left) and Matthew Walter mapped the evolution of cancer cells in seven patients with myelodysplastic syndromes who later died of leukemia.

Using whole-genome sequencing, researchers have uncovered new clues to the genetic alterations underlying acute myeloid leukemia (AML) that arises in patients who were previously diagnosed with a myelodysplastic syndrome. Myelodysplastic syndromes develop when the bone marrow stops...

Acute Myeloid Leukemia (AML) Treatment in Adults (Beyond the Basics)

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Acute myeloid leukemia (AML) is a type of cancer of blood and bone marrow cells. It affects a group of white blood cells called myeloid cells. Normally, myeloid and other blood cells are produced in the bone marrow (the spongy area in the middle of bones) in a carefully controlled fashion. In someone with AML, the blood cell production process is abnormal and large numbers of immature myeloid cells are produced and may be released into the blood stream...

What Do Fats Do in the Body?

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What Do Fats Do in the Body?

It's common knowledge that too much cholesterol and other fats can lead to disease, and that a healthy diet involves watching how much fatty food we eat. However, our bodies need a certain amount of fat to function—and we can't make it from scratch.

Triglycerides, cholesterol and other essential fatty acids—the scientific term for fats the body can't make on its own—store energy, insulate us and protect our vital organs. They act as messengers, helping...

Spine Basics

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Understanding your spine and how it works can help you better understand some of the problems that occur from aging or injury.

Many demands are placed on your spine. It holds up your head, shoulders, and upper body. It gives you support to stand up straight, and gives you flexibility to bend and twist. It also protects your spinal cord.


Spinal Curves

Your spine is made up of three segments. When viewed from the side, these segments form three natural curves. The "c-shaped" curves of...