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Mon12092019

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Back Bones, Joints and Muscles Connective Tissue Disorders

Connective Tissue Disorders

Genetics Home Reference: Systemic scleroderma

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Systemic scleroderma is an autoimmune disorder that affects the skin and internal organs. Autoimmune disorders occur when the immune system malfunctions and attacks the body's own tissues and organs. The word "scleroderma" means hard skin in Greek, and the condition is characterized by the buildup of scar tissue (fibrosis) in the skin and other organs. The condition is also called systemic sclerosis because the fibrosis can affect organs other than the skin. Fibrosis is due to the excess...

Systemic scleroderma is an autoimmune disorder that affects the skin and internal organs. Autoimmune disorders occur when the immune system malfunctions and attacks the body's own tissues and organs. The word "scleroderma" means hard skin in Greek...

Genetics Home Reference: Pseudoxanthoma elasticum

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Pseudoxanthoma elasticum is a progressive disorder that is characterized by accumulated deposits of calcium (calcification) and other minerals in elastic fibers, which are a component of connective tissue. Connective tissue provides strength and flexibility to structures throughout the body.

Calcification can affect elastic fibers in the skin, eyes, and blood vessels, and less frequently in other areas such as the digestive tract. As a result, people with pseudoxanthoma elasticum may...